Depending on the acquisition of developmental competence, the expression of genes for β-1,3-glucan synthase and chitin synthase was affected in different ways by Aspergillus nidulans LAMMER kinase. LAMMER kinase deletion, ΔlkhA, led to decrease in β-1,3-glucan, but increase in chitin content. The ΔlkhA strain was also resistant to nikkomycin Z.
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http://dx.doi.org/10.5941/MYCO.2014.42.4.422 | DOI Listing |
Plant Physiol Biochem
September 2024
Key Laboratory of Biology and Sustainable Management of Plant Diseases and Pests of Anhui Higher Education Institutes, Hefei, 230036, PR China; College of Plant Protection, Anhui Agricultural University, Hefei, 230036, PR China. Electronic address:
Cell cycle progression, autophagic cell death during appressorium development, and ROS degradation at the infection site are important for the development of rice blast disease. However, the association of cell cycle, autophagy and ROS detoxification remains largely unknown in M. oryzae.
View Article and Find Full Text PDFFront Cell Infect Microbiol
May 2024
Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup, Jeonbuk, Republic of Korea.
Dual-specificity LAMMER kinases are highly evolutionarily conserved in eukaryotes and play pivotal roles in diverse physiological processes, such as growth, differentiation, and stress responses. Although the functions of LAMMER kinase in fungal pathogens in pathogenicity and stress responses have been characterized, its role in , a human fungal pathogen and a model yeast of basidiomycetes, remains elusive. In this study, we identified a homologous gene and constructed a strain with a deleted and a complemented strain.
View Article and Find Full Text PDFJ Microbiol
January 2024
Department of Microbiology and Molecular Biology, College of Bioscience and Biotechnology, Chungnam National University, Daejeon, 34134, Republic of Korea.
It was reported that LAMMER kinase in Schizosaccharomyces pombe plays an important role in cation-dependent and galactose-specific flocculation. Analogous to other flocculating yeasts, when cell wall extracts of the Δlkh1 strain were treated to the wild-type strain, it displayed flocculation. Gas2, a 1,3-β-glucanosyl transferase, was isolated from the EDTA-extracted cell-surface proteins in the Δlkh1 strain.
View Article and Find Full Text PDFMycobiology
October 2023
Laboratory of Cellular Differentiation, Department of Microbiology and Molecular Biology, College of Bioscience and Biotechnology, Chungnam National University, Daejeon, Republic of Korea.
Lkh1, a LAMMER kinase homolog in the fission yeast , acts as a negative regulator of filamentous growth and flocculation. It is also involved in the response to oxidative stress. The deletion mutant displays slower cell growth, shorter cell size, and abnormal DNA content compared to the wild type.
View Article and Find Full Text PDFProc Biol Sci
November 2022
Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.
'Evolve and resequence' (E&R) studies in have identified many candidate loci underlying the evolution of ageing and life history, but experiments that validate the effects of such candidates remain rare. In a recent E&R study we have identified several alleles of the LAMMER kinase () as candidates for evolutionary changes in lifespan and fecundity. Here, we use two complementary approaches to confirm a functional role of in life-history evolution.
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