Aldosterone deficiency after unilateral adrenalectomy for Conn's syndrome: a case report and literature review.

Int J Surg Case Rep

Department of Surgery, St. Paul's Hospital, Vancouver, British Columbia, Canada. Electronic address:

Published: February 2015

Introduction: Approximately 35% of cases of Conn's syndrome (primary aldosteronism) result from a solitary functioning adrenal adenoma, and these patients are best managed by adrenalectomy. Postoperative hypoaldosteronism after unilateral adrenalectomy is uncommon.

Case Presentation: We present a case and literature review of hypoaldosteronism after unilateral adrenalectomy for Conn's syndrome, which demonstrates the insidious and sometimes delayed presentation.

Discussion: In this clinical case we summarize the previously published cases of post-adrenalectomy hypoaldosteronism based on a PUBMED and EBSCOhost search of all peer-reviewed publications (original articles and reviews) on this topic. A few cases of aldosterone insufficiency post-adrenalectomy for Conn's syndrome were identified. The etiological factors for prolonged selective suppression of aldosterone secretion after unilateral adrenalectomy remain unclear.

Conclusion: It is important to be aware of the risk of postoperative hypoaldosteronism in this patient population. Close postoperative follow-up is necessary and strongly recommended, especially in patients with certain risk factors. Patients may need mineralocorticoid supplementation during this period.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336421PMC
http://dx.doi.org/10.1016/j.ijscr.2015.01.013DOI Listing

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