Objective: To explore the prevalence of maternal near miss (MNM) and adverse pregnancy outcomes in Zhejiang province by MNM surveillance system.
Methods: A cross-sectional study was conducted during 2012 and 2013. All MNM cases were recruited from the MNM surveillance system. The information was reported by direct network report system, including personal information, obstetric complications, maternal rescue measures, rescue process and severe maternal and perinatal outcomes.
Results: A total of 826 MNM patients were recruited. The MNM rate was 5.6 cases/1 000 live births (LB). Maternal gestational hypertension was the most common disease among MNM, accounting for 19.9% (n = 164) . The second prevalent one was insufficient uterine contraction, accounting for 19.6% (n = 162). Placenta previa was the third one accounting for 17.7% (n = 146). Among adverse pregnancy outcomes, 139 cases underwent hysterectomy (n = 139, 16.8%). There were 81 perinatal deaths with a perinatal mortality of 10.4%. And 279 cases (39.9%) were preterm.
Conclusion: MNM surveillance system is valuable for grasping the prevalence of MNM. And it helps to reduce MNM rate by improving the quality of obstetrics and lower the preterm rate and perinatal mortality.
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Ecotoxicol Environ Saf
January 2025
Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang 110004, PR China. Electronic address:
Cigarette smoke (CS) has detrimental effects on placental growth and embryo development, but the underlying mechanisms remain unclear. This study aims to investigate the impact of CS on trophoblast cell proliferation and regulated cell death (RCD) by examining its interference with iron-sulfur cluster (ISC) proteins and the CIA pathway. Exposure to CS disrupted the cytosolic ISC assembly (CIA) pathway, downregulated ISC proteins, and decreased ISC maturation in the placenta of rats exposed to passive smoking.
View Article and Find Full Text PDFPeerJ
January 2025
Center of Reproductive Medicine, Qingdao Women and Children's Hospital, Qingdao, China.
Background: Group B streptococcus (GBS) colonization in pregnant women is associated with adverse perinatal outcomes, including stillbirth. This meta-analysis investigated the relationship between maternal rectovaginal GBS colonization and the risk of stillbirth.
Methods: We conducted a comprehensive literature search across several databases, including PubMed, Embase, Web of Science, Wanfang, and China National Knowledge Infrastructure, covering studies published from the inception of the database until September 9, 2024.
Clin Case Rep
January 2025
Jimma Medical Center, Department of Gynecology and Obstetrics Jimma University Jimma Ethiopia.
The twin reversed arterial perfusion (TRAP) sequence is a rare complication associated with monochorionic twins. It is characterized by blood flow from the umbilical artery of the normal (pump) twin to the umbilical artery of the abnormal (acardiac) twin via artery-to-artery anastomosis. This condition is associated with 100% mortality in the acardiac twin and a high rate of perinatal morbidity and mortality in the pump twin, primarily due to intrauterine hypoxic injury, heart failure, and prematurity.
View Article and Find Full Text PDFEnviron Epidemiol
February 2025
Department of Public Health Sciences, University of Rochester Medical Center, Rochester, New York.
Background: Sex steroid hormones are critical for maintaining pregnancy and optimal fetal development. Air pollutants are potential endocrine disruptors that may disturb sex steroidogenesis during pregnancy, potentially leading to adverse health outcomes.
Methods: In the Environmental influences on Child Health Outcomes Understanding Pregnancy Signals and Infant Development pregnancy cohort (Rochester, NY), sex steroid concentrations were collected at study visits in early-, mid-, and late-pregnancy in 299 participants.
Am J Transl Res
December 2024
Department of Pediatrics, Xi'an International Medical Center Hospital No. 777 Xitai Road, Chang'an District, Xi'an 710000, Shaanxi, China.
Objective: This study aimed to identify factors influencing the prognosis of children with severe pneumonia (SP) after fiberoptic bronchoscopic bronchoalveolar lavage (BAL).
Methods: The clinical data of 155 children with SP treated with fiberoptic bronchoscopic BAL at Xi'an International Medical Center Hospital between January 2022 and January 2024 were retrospectively analyzed. Children were categorized into the survival group (n = 122) and the death group (n = 33) according to their clinical outcomes within 28 days after treatment.
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