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http://dx.doi.org/10.1016/j.ophtha.2014.11.019 | DOI Listing |
J Neuroinflammation
January 2025
Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21231, USA.
Background: The retinal degenerative diseases retinitis pigmentosa (RP) and atrophic age- related macular degeneration (AMD) are characterized by vision loss from photoreceptor (PR) degeneration. Unfortunately, current treatments for these diseases are limited at best. Genetic and other preclinical evidence suggest a relationship between retinal degeneration and inflammation.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
College of Engineering and Technology, Northeast Forestry University, Harbin 150040, PR China. Electronic address:
The demand for extended shelf life and food safety in the food industry continues to rise. At the same time, the environmental burden of traditional plastic packaging materials is becoming increasingly serious. Therefore, in this study, an intelligent bilayer film with a pH-sensitive inner indicator film based on Artemisia Sphaerocephala Krasch.
View Article and Find Full Text PDFCarbohydr Polym
March 2025
Plant Fiber Material Science Research Center, State Key Laboratory of Pulp and Paper Engineering, School of Light Industry and Engineering, South China University of Technology, Guangzhou 510640, China; Guangdong Provincial Key Laboratory of Plant Resources Biorefinery, No. 100, West Outer Ring Road, Guangzhou University Town, Panyu District, Guangzhou 510006, China.
Ancient documents and artworks are invaluable cultural heritage artworks that require careful preservation. Traditional methods for assessing their physical and chemical properties-such as tearing index, tensile index, water absorption, and pH-are often destructive, risking irreversible damage. This study introduces a novel, non-destructive approach using Short-Wave Near-Infrared (SWNIR) hyperspectral imaging (HSI) combined with advanced machine learning models.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Department of Radiology, Nanjing Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, 305 East Zhongshan Road, Nanjing, 210002, China.
Pyroptosis is a key mode of programmed cell death during the early stages following acute myocardial infarction (AMI), driving immune-inflammatory responses. Cardiac resident macrophages (CRMs) are the primary mediators of cardiac immunity, and they serve a dual role through their shaping of both myocardial injury and post-AMI myocardial repair. To appropriately regulate AMI-associated inflammation, HM4oRL is herein designed, an innovative bifunctional therapeutic nanoplatform capable of inhibiting cardiomyocyte pyroptosis while reprogramming inflammatory signaling.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
January 2025
Vitreous Retina Macula Consultants of New York, New York, United States.
Purpose: The purpose of this study was to develop ground-truth histology about contributors to variable fundus autofluorescence (FAF) signal and thus inform patient selection for treating geographic atrophy (GA) in age-related macular degeneration (AMD).
Methods: One woman with bilateral multifocal GA, foveal sparing, and thick choroids underwent 535 to 580 nm excitation FAF in 6 clinic visits (11 to 6 years before death). The left eye was preserved 5 hours after death.
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