Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290178 | PMC |
| http://dx.doi.org/10.4103/2229-5178.146193 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Successful treatment of porokeratosis ptychotropica with abrocitinib.
Int J Dermatol
December 2024
Department of Dermatology, The Affiliated Chengdu 363 Hospital of Southwest Medical University, Chengdu, Sichuan, China.
Autosomal dominant genodermatoses in adults being heralded by superimposed skin lesions in children.
Am J Med Genet C Semin Med Genet
June 2023
Department of Dermatology, Medical Center-University of Freiburg, Freiburg, Germany.
Article Synopsis
- Autosomal dominant skin disorders can exhibit pronounced mosaic involvement in neonates, stemming from early loss of heterozygosity in the embryo shortly after fertilization.
- Some syndromes, like Brooke-Spiegler and Hornstein-Knickenberg, show early-onset symptoms that can foreshadow later, more widespread manifestations of the disorder.
- Conditions like glomangiomatosis and Darier disease demonstrate that neonatal mosaic lesions can be early indicators of nonsegmental skin issues emerging much later in life.
Porokeratosis: a differential diagnosis to consider in benign lichenoid keratosis.
Int J Clin Exp Pathol
February 2022
Dermatology Division, Department of Anatomical Pathology, Pathlab 829 Cameron Road, Tauranga 3112, New Zealand.
Porokeratosis is a disorder of keratinization with many clinical variants. The histological hallmark feature of porokeratosis is a cornoid lamella. Other accompanying features include lichenoid inflammation, atrophy towards the centre of the lesion, dermal cytoid bodies, and adjacent lichenoid changes.
View Article and Find Full Text PDFPorokeratosis: An enigma beginning to unravel.
Indian J Dermatol Venereol Leprol
May 2022
Talwar Skin Centre, Lucknow, Uttar Pradesh, India.
Porokeratosis is a keratinization disorder with unclear etiopathogenesis, varied clinical presentation and characteristic histopathology, and is usually unresponsive to current therapeutic options. Until now, it was considered to be a clonal disorder with immunity, ultra violet radiation and other factors playing important roles in etiopathogenesis. It is now known that abnormalities in the mevalonate pathway are responsible for this clonal keratinization abnormality.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!