AI Article Synopsis
- Rabies is a significant public health issue in developing countries, especially when typical symptoms like hydrophobia appear after a known animal bite.
- A case was reported of a 6-year-old boy experiencing atypical symptoms, including febrile seizure and agitation, 17 days post dog bite despite receiving rabies postexposure prophylaxis.
- Unfortunately, he died, and rabies encephalitis was confirmed through brain biopsies using fluorescent antibody techniques.
Article Abstract
Rabies remains a serious public health problem in many developing countries. The diagnosis is easy when a non-immunised patient presents with hydrophobia and hypersalivation after a bite by a known rabid animal but more difficult when a patient presents atypical symptoms after having received rabies postexposure prophylaxis. Rabies postexposure prophylaxis failure is rare. We report a case of a 6-year-old boy who presented febrile seizure with agitation and cerebellar signs, without hydrophobia or hypersalivation, 17 days after a dog bite. Despite four doses of rabies vaccine and immunoglobulin, he died. Diagnostic confirmation of rabies encephalitis was made in post mortem on brain biopsies by fluorescent antibody technique.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307068 | PMC |
| http://dx.doi.org/10.1136/bcr-2014-206191 | DOI Listing |
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