Visual perception of object attributes such as surface lightness is crucial for successful interaction with the environment. How the visual system assigns lightness to image regions is not yet understood. It has been shown that the context in which a surface is embedded influences its perceived lightness, but whether that influence involves predominantly low-, mid-, or high-level visual mechanisms has not been resolved. To answer this question, we measured whether perceptual attributes of target image regions affected their perceived lightness when they were placed in different contexts. We varied the sharpness of the edge while keeping total target flux fixed. Targets with a sharp edge were consistent with the perceptual interpretation of a surface, and in that case, observers perceived significant brightening or darkening of the target. Targets with blurred edges rather appeared to be spotlights instead of surfaces; for targets with blurred edges, there was much less of a contextual effect on target lightness. The results indicate that the effect of context on the lightness of an image region is not fixed but is strongly affected by image manipulations that modify the perceptual attributes of the target, implying that a mid-level scene interpretation affects lightness perception.
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http://dx.doi.org/10.1167/15.1.15 | DOI Listing |
Nat Commun
January 2025
State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
The relative contributions of mutation rate variation, selection, and recombination in shaping genomic variation in bacterial populations remain poorly understood. Here we analyze 3318 Yersinia pestis genomes, spanning nearly a century and including 2336 newly sequenced strains, to shed light on the patterns of genetic diversity and variation distribution at the population level. We identify 45 genomic regions ("hot regions", HRs) that, although comprising a minor fraction of the genome, are hotbeds of genetic variation.
View Article and Find Full Text PDFOecologia
January 2025
Plant Evolutionary Ecology, Institute of Ecology, Evolution and Diversity, Faculty of Biological Sciences, Goethe University Frankfurt, Max-Von-Laue-Str. 13, 60438, Frankfurt am Main, Germany.
Rapid environmental changes across Europe include warmer and increasingly variable temperatures, changes in soil nutrient availability, and pollinator decline. These abiotic and biotic changes can affect natural plant populations and force them to optimize resource use against competitors. To date, the evolution of competitive ability in the context of changes in nutrient availability remains understudied.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
P. Roy and Diana T. Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, Pennsylvania 19104, United States.
Photocatalytic C-H activation is an emerging area of research. While cerium chloride photocatalysts have been extensively studied, the role of alcohol additives in these systems remains a subject of ongoing discussion. It was demonstrated that the photocatalyst [NEt][CeCl] () produces •Cl and added alcohols exhibit zero-order kinetics.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Background: The Apolipoprotein E ε4 (APOE-ε4) allele is common in the population, but acts as the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Despite the strength of the association, there is notable heterogeneity in the population including a strong modifying effect of genetic ancestry, with the APOE-ε4 allele showing a stronger association among individuals of European ancestry (EUR) compared to individuals of African ancestry (AFR). Given this heterogeneity, we sought to identify genetic modifiers of APOE-ε4 related to cognitive decline leveraging APOE-ε4 stratified and interaction genome-wide association analyses (GWAS).
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Homi Bhabha National Institute, Mumbai, Maharashtra, India.
Background: Recent advances in understanding the regulatory networks implicated in Alzheimer's Disease (AD) evinces the involvement of long non-coding RNAs (lncRNAs) as crucial regulatory players. The present study explores the role played by maternally imprinted lncRNA XIST in regulating the sex-biased prevalence of AD.
Method: With whole transcriptomic sequencing data from the hippocampal RNA of post-mortem AD brains from humans and APP/PS1 mice, the altered expression of XIST in AD was studied.
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