Phage display screening of a surface-immobilized adenine derivative led to the identification of a heptameric peptide with selectivity for adenine as demonstrated through quartz crystal microbalance (QCM) studies. The peptide demonstrated a concentration dependent affinity for an adeninyl moiety decorated surface (K D of 968 ± 53.3 μM), which highlights the power of piezoelectric sensing in the study of weak interactions.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264375 | PMC |
| http://dx.doi.org/10.3390/bios4020137 | DOI Listing |
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