Seroepidemiology of Toxocara infection in patients with vision impairment and blindness in durango, Mexico.

J Clin Med Res

Institute for Scientific Research "Dr. Roberto Rivera-Damm", Juarez University of Durango State, Avenida Universidad S/N, 34000 Durango, Mexico.

Published: March 2015

Background: Toxocara infection is a cause of vision impairment and blindness. We aimed to determine the seroprevalence and correlates of Toxocara infection in patients suffering from vision impairment and blindness in Durango City, Mexico.

Methods: Through a cross-sectional seroprevalence study, 204 patients with vision impairment and 19 blind patients were studied for the presence of anti-Toxocara IgG antibodies in Durango City, Mexico. Seroprevalence association with socio-demographic, housing, clinical, and behavioral characteristics of participants was also investigated.

Results: Five (2.5%) of the 204 patients with vision impairment, and none of the 19 patients with blindness were positive for anti-Toxocara IgG antibodies. In total, five of the 223 (2.2%) patients were positive for anti-Toxocara IgG antibodies. Seropositivity to Toxocara was not associated with age, sex, educational level, socio-economic status, presence of underlying diseases or behavioral characteristics of the patients. In contrast, multivariate analysis showed that Toxocara seropositivity was associated with living in a house with soil floor (odds ratio (OR) = 11.14; 95% confidence interval (CI): 1.57 - 78.74; P = 0.01).

Conclusions: This is the first report of Toxocara exposure in patients with vision impairment and blindness in Mexico, and of an association of Toxocara exposure with living in a house with soil floors. Results suggest a low Toxocara exposure in these patients in Durango, Mexico. The risk factor associated with Toxocara exposure identified in this study warrants for further investigation.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285064PMC
http://dx.doi.org/10.14740/jocmr2032wDOI Listing

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