Objective: To analyze surgical methods and medical costs for patients with uterine leiomyomas treated by hysterectomy in mainland China in 2010.
Methods: In a cross-sectional study, data for patients hospitalized with uterine leiomyomas and treated with hysterectomy were obtained from pooled medical records of 3030 hospitals. Type of surgery was categorized into abdominal hysterectomy (AH), laparoscopic hysterectomy (LH), and total vaginal hysterectomy (TVH). Length of stay and medical costs were analyzed for each procedure and in four types of hospital.
Results: Among 147 966 patients, 129 668 (87.6%) underwent AH, 9164 (6.2%) LH, and 9134 (6.2%) TVH. The total cost and operative cost were lowest for the AH group and highest for the LH group (P<0.001). Length of stay was shortest for TVH groups in all four types of hospital (P<0.001). The ratios between the frequencies of the three procedures were significantly different among the four types of hospital (P<0.001).
Conclusion: In mainland China, AH remains the main surgical route of hysterectomy for patients with uterine leiomyomas. The length of stay was shortest among patients undergoing TVH, but the mean stay was still more than 9days.
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http://dx.doi.org/10.1016/j.ijgo.2014.10.031 | DOI Listing |
Radiol Case Rep
March 2025
Tunis Maternity and Neonatology Center, Department 'C' of Gynecology and Obstetrics, Tunis, Tunisia.
This case report describes a rare instance of intraperitoneal rupture in a redegenerated uterine fibroid during pregnancy. A 38-year-old woman at 38 weeks gestation, with a history of a single pregnancy, presented with mild pelvic pain persisting through late pregnancy. An emergency caesarean section was performed due to acute fetal distress during labor.
View Article and Find Full Text PDFDrug Des Devel Ther
January 2025
People's Hospital of Zhengzhou University, Zhengzhou, Henan, 45003, People's Republic of China.
Background: Both intramural myomas and thin endometrium exert a detrimental influence on the outcomes of assisted reproductive technology (ART). The downregulation of gonadotropin releasing hormone agonists (GnRH-a) is regarded as an effective approach to reducing the size of intramural fibroids and enhancing endometrial receptivity. Consequently, we conducted this study to assess whether the GnRH-a combined with hormone replacement therapy (GnRH-a-HRT) can improve reproductive outcomes in frozen embryo transfer cycles for patients with a thin endometrium (≤7 mm) and intramural fibroids.
View Article and Find Full Text PDFMedicine (Baltimore)
November 2024
Department of Cardiology, Center Hospital of Shandong First Medical University, Jinan, China.
This study employs Mendelian randomization (MR) approach to investigate the potential causal association between genetic variants associated with gut microbiota, inflammatory factors, and the risk of uterine fibroids development. We extracted data on 211 types of gut microbiota, 91 inflammatory factors, and uterine fibroids occurrence from genome-wide association studies and applied the inverse-variance weighted (IVW) method for analysis. To further assess the robustness of our MR analysis, we conducted sensitivity tests including Cochrane's Q test, the MR-Egger intercept test, the MR-PRESSO global test, and a leave-one-out analysis.
View Article and Find Full Text PDFEnviron Health Perspect
January 2025
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
Background: Uterine fibroids disproportionately affect Black women, and exposure to chemicals from hair relaxers or straighteners ("straighteners") may contribute to fibroid development.
Objectives: We examined the association between straightener use and prevalent young-onset uterine fibroids (diagnosed before age 36 y), as well as incident fibroids (diagnosed age 36-60 y), with a focus on Black women. We also examined differences in associations across birth cohorts as proxies for formulation changes.
Cochrane Database Syst Rev
June 2024
The Jessop Wing and Royal Hallamshire Hospital, Sheffield Teaching Hospitals, Sheffield, UK.
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the effects of surgery and minimally invasive treatments for uterine fibroids.
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