Bicarbonate dialysis is the treatment modality of choice for correction of metabolic acidosis in chronic renal failure. However, improper selection of dialysate concentrate can result in life-threatening human errors. We report a case of iatrogenic severe hypernatremia (sodium 207 mEq/L) and severe metabolic acidosis (pH 6.65) that resulted due to accidental use of inappropriate bicarbonate concentrate for hemodialysis treatment. There was successful recovery in this patient with no neurological sequelae. To the best of our knowledge, this is the first case report in adults of severe hypernatremia along with severe metabolic acidosis due to error in the preparation of dialysis fluid.
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http://dx.doi.org/10.4103/1319-2442.148754 | DOI Listing |
Trop Anim Health Prod
December 2024
Jiangxi Province Key Laboratory of Animal Nutrition/Engineering Research Center of Feed Development, Jiangxi Agricultural University, Nanchang, 330045, China.
Rumen acidosis is a common nutritional metabolic disease in ruminants, and the developing of feed additives to prevent this disorder has great application prospect. This study was conducted to investigate the effects of dietary niacin supplementation with different concentrate to roughage ratio on rumen fermentation evaluated by simulated rumen fermentation in vitro and in vivo. The cattle fed with basal feed (dietary concentrate-to-forage ratio was 5: 5) and high concentrate feed (dietary concentrate-to-forage ratio was 8: 2) were defined as Control stage and HC stage, respectively.
View Article and Find Full Text PDFAnn Med
December 2025
Intensive Care Unit, State Institute for Infectious Diseases São Sebastião, Rio de Janeiro, Rio de Janeiro, Brazil.
Background/objectives: Pregnant and postpartum women have a higher risk for developing severe Covid-19 and other clinical and obstetric complications. This study aims to evaluate the frequency of metabolic acidosis with elevated anion gap and describe a case series of euglycemic ketoacidosis (EKA) in pregnant and postpartum women with severe confirmed or suspected Covid-19.
Materials And Methods: Observational retrospective study carried in a reference intensive care unit from May 2020 to June 2022.
Infect Drug Resist
December 2024
Pulmonary Diseases Department, The Third People's Hospital of Shenzhen, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, People's Republic of China.
Background: Tuberculosis (TB) among women and infants during the perinatal period is not rare, particularly in countries with a high TB burden. And the risk would increase significantly following in vitro fertilization-embryo transfer (IVFET). Worse still, TB in this stage is apt to develop into severe forms in women and neonates, such as disseminated TB or tuberculous meningitis (TBM).
View Article and Find Full Text PDFAerosp Med Hum Perform
November 2024
Background: Ejection seats are designed to be a lifesaving device for aircrew in emergencies. Modern ejection seats are widely prevalent in fighter and bomber aircraft and are occasionally associated with acceleration injury from axial loading (Gz) during the catapult phase of ejection, limb flail injury due to windblast, or parachute landing fall, especially if the ejection is outside of the seat's performance envelope.
Case Report: We present the first known case in the medical literature of a military pilot who survived a low-altitude, high-angulation (>90° of bank angle) ejection where the pilot's ejection seat parachute did not deploy due to contact with the ground before completion of the ejection sequence.
Chemosphere
December 2024
Department of Life Science, School of Life Science, National Taiwan Normal University, Taipei, Taiwan. Electronic address:
Acidification of freshwater due to human activities is a widespread environmental problem. Its effects on the sensorimotor responses of fish, particularly during embryonic stages, may affect population fitness. To address this, zebrafish embryos were exposed to water at pH 7, 5 and 4.
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