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The increasing value of plant-made proteins. | LitMetric

The increasing value of plant-made proteins.

Curr Opin Biotechnol

Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria. Electronic address:

Published: April 2015

The production of high-value proteins in plants is maturing, as shown by the recent approval of innovative products and the latest studies that showcase plant-based production systems using technologies and approaches that are well established in other fields. These include host cell engineering, medium optimization, scalable unit operations for downstream processing (DSP), bioprocess optimization and detailed cost analysis. Product-specific benefits of plant-based systems have also been exploited, including bioencapsulation and the mucosal delivery of minimally processed topical and oral products with a lower entry barrier than pharmaceuticals for injection. Success stories spearheaded by the FDA approval of Elelyso developed by Protalix have revitalized the field and further interest has been fueled by the production of experimental Ebola treatments in plants.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485345PMC
http://dx.doi.org/10.1016/j.copbio.2014.12.008DOI Listing

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