Soy food intake and treatment outcomes of women undergoing assisted reproductive technology.

Fertil Steril

Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

Published: March 2015

AI Article Synopsis

  • The study examines how dietary phytoestrogens, particularly soy isoflavones, affect clinical outcomes for women undergoing infertility treatments using assisted reproductive technology (ART).
  • It involved 315 women who participated in 520 ART cycles at a fertility center between 2007 and 2013, and measured outcomes such as implantation, clinical pregnancy, and live birth rates.
  • Results showed that higher intake of soy isoflavones was linked to increased live birth rates, suggesting that dietary soy could enhance the success of ART treatments.

Article Abstract

Objective: To study the relation of dietary phytoestrogens intake and clinical outcomes of women undergoing infertility treatment with the use of assisted reproductive technology (ART).

Design: Prospective cohort study.

Setting: Fertility center.

Patient(s): A total of 315 women who collectively underwent 520 ART cycles from 2007 to 2013.

Intervention(s): None.

Main Outcome Measure(s): Implantation, clinical pregnancy, and live birth rates per initiated cycle.

Result(s): Soy isoflavones intake was positively related to live birth rates in ART. Compared with women who did not consume soy isoflavones, the multivariable-adjusted odds ratios of live birth (95% confidence interval) for women in increasing categories of soy isoflavones intake were 1.32 (0.76-2.27) for women consuming 0.54-2.63 mg/d, 1.87 (1.12-3.14) for women consuming 2.64-7.55 mg/d, and 1.77 (1.03-3.03) for women consuming 7.56-27.89 mg/d.

Conclusion(s): Dietary soy intake was positively related to the probability of having a live birth during infertility treatment with ART.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346414PMC
http://dx.doi.org/10.1016/j.fertnstert.2014.12.104DOI Listing

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