F-class cells: new routes and destinations for induced pluripotency.

Cell Stem Cell

Division of Hematology/Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medical College, New York, NY 10021, USA. Electronic address:

Published: January 2015

A series of five related publications describe an alternative pluripotent state that is dependent on continuous high levels of exogenous reprogramming factor expression. A comprehensive effort to molecularly compare the acquisition of this state to induced pluripotency aims at providing new insights into the mechanisms underlying cellular reprogramming.

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Source
http://dx.doi.org/10.1016/j.stem.2014.12.007DOI Listing

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