Two papers by McEwan et al. (McEwan et al., 2015a, 2015b) identify interactions of PLEKHM1 with autophagosome-associated Atg8 proteins and Salmonella typhimurium effector, SifA, linking autophagy and the Salmonella-containing vacuole (SCV) to the endolysosomal Rab7/HOPS-regulated tethering machinery.
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PLEKHM1: a multiprotein adaptor for the endolysosomal system.
Mol Cell
January 2015
Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address:
Two papers by McEwan et al. (McEwan et al., 2015a, 2015b) identify interactions of PLEKHM1 with autophagosome-associated Atg8 proteins and Salmonella typhimurium effector, SifA, linking autophagy and the Salmonella-containing vacuole (SCV) to the endolysosomal Rab7/HOPS-regulated tethering machinery.
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