Chemical investigation of the ethanol extract of the roots of Cudrania cochinchinensis led to the isolation of a new flavonoid, (6S,12S,13R)-1-methoxy cyanomaclurin (1), together with seven known compounds, 1,3,5-trihydroxy-4-(3'-hydroxy-3'-methylbutyl)xanthone (2), 1,3,6-trihydroxy-4-prenylxanthone (3), 1,3,6,7-tetrahydroxyxanthone (4), 1,3,5,6-tetrahydroxyxanthone (5), 1,3,6-trihydroxy-5-methoxyxanthone (6), resveratrol (7) and oxyresveratrol (8). The structure of compound 1 was elucidated on the basis of 1D and 2D NMR spectra and the HR-ESI-MS data. The absolute stereochemistry was deduced via Rh2(OCOCF3)4-induced CD and NOESY spectra.
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http://dx.doi.org/10.1080/14786419.2014.997234 | DOI Listing |
J Asian Nat Prod Res
November 2024
Anti-infective Agent Creation Engineering Research Centre of Sichuan Province, School of Pharmacy, Chengdu University, Chengdu 610106, China.
Lupalbigenin () is an antibacterial isoflavone isolated from (Lour.) Corner (Moraceae). In this study, we achieved the first gram-scale synthesis of lupalbigenin () from commercially available genistein (), with a yield of 47.
View Article and Find Full Text PDFJ Pharm Biomed Anal
May 2024
School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, PR China; Engineering Center of State Ministry of Education for Standardization of Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, PR China. Electronic address:
Radix Cudramiae, the dried root of Cudrania cochinchinensis (Lour.) Kudo et Masam., is a valuable ethnomedicine with outstanding antihepatitis activity.
View Article and Find Full Text PDFBMC Complement Med Ther
June 2023
Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand.
Background And Aims: The purpose of this study was to investigate the biological properties of Kae-Lae (Maclura cochinchinensis (Lour.) Corner), a traditional medicinal plant used in Ayurvedic recipes in Thailand. To achieve this objective, heartwood samples were collected from 12 sources across Thailand.
View Article and Find Full Text PDFInflammopharmacology
February 2023
School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, 80160, Thailand.
The anti-inflammatory actions of phytochemicals have attracted much attention due to the current state of numerous inflammatory disorders. Thai traditional medicine uses Maclura cochinchinensis (Lour.) Corner to treat chronic fever and various inflammatory diseases, as well as to maintain normal lymphatic function.
View Article and Find Full Text PDFNat Prod Res
December 2022
Natural Products Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen, Thailand.
Three new furanoxanthones, macochinxanthones A-C (-) and sixteen known xanthones (-) were isolated from the roots of Their structures were elucidated by spectroscopic analysis including NMR, UV and IR, as well as mass spectrometry. Chiral-phase HPLC analysis of - revealed that they were scalemic mixtures with an enantiomeric excess (ee) of 0.05%, 36.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!