This study investigates the contamination of foods and surfaces with Clostridium difficile in a single nursing home. C. difficile PCR-ribotype 078 was found in one food sample and in none of the tested surfaces. These results indicate that food and surfaces are an unlikely source of C. difficile infection in this setting.
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http://dx.doi.org/10.1016/j.anaerobe.2015.01.001 | DOI Listing |
PLoS One
January 2025
Department of Pharmacy, Chongqing General Hospital, Chongqing University, Chongqing, China.
Background: Acetaminophen serves as a standard antipyretic and analgesic agent in the intensive care unit (ICU). However, the association between its administration and acute kidney injury (AKI) among critically ill patients remains controversial, particularly lacking research in patients with Clostridioides difficile infection (CDI). Our aim was to explore the potential relationship between early acetaminophen administration and AKI in critically ill patients with concurrent CDI.
View Article and Find Full Text PDFGut Microbes
December 2025
Medical School, University of Minnesota, Minneapolis, MN, USA.
Diet constitutes a major source of nutrient flow to the gut microbes. As such, it can be used to help shape the gut microbiome. Fecal microbiota transplantation (FMT) is an increasingly promising therapy in disease states beyond recurrent infection, but diet is largely overlooked for its potential to help optimize this therapy.
View Article and Find Full Text PDFMicroorganisms
December 2024
Division of Gastroenterology, Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Incheon 22332, Republic of Korea.
Recently, fecal microbiota transplantation (FMT) has been introduced as an effective treatment option for infection (CDI). However, the risk factors associated with FMT treatment failure have not been well demonstrated. Therefore, we aimed to investigate the risk factors of treatment failure or recurrence after FMT for CDI.
View Article and Find Full Text PDFMicroorganisms
December 2024
Department of Epidemiology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
infection (CDI) is one of the main causes of morbidity associated with antibiotic use, producing both healthcare-associated infections and community infections. This study aims to describe the epidemiological characteristics, the clinical outcomes, previous antibiotic exposure, and other risk factors of hospitalized patients with CDI in a tertiary infectious disease hospital in Bucharest, Romania. We performed a descriptive analysis based on four-year surveillance data, collected in a tertiary infectious disease hospital in Bucharest, Romania.
View Article and Find Full Text PDFMicroorganisms
November 2024
Department of Clinical Microbiology, Infection Prevention and Control, University Hospital Centre Zagreb, Kispaticeva st. 12, 10000 Zagreb, Croatia.
We investigated the intra-hospital distribution of strains by whole-genome sequencing (WGS) of isolates collected in 2022 at the University Hospital Centre (UHC) Zagreb. In total, 103 patients with first-episode CDI in 2022 at UHC Zagreb were included, based on the screening stool antigen test for GDH (RidaQuick CD GDH; R-Biopharm AG, Germany), confirmed by Eazyplex assays (Eazyplex CD assay; AmplexDiagnostics GmbH, Germany) specific for A, B, and binary toxins. Demographic and clinical data were retrospectively analyzed from electronic medical records.
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