Steady-state visual evoked potential (SSVEP)-based brain-computer interfaces (BCIs) have potential to provide a fast communication channel between human brain and external devices. In SSVEP-based BCIs, Canonical Correlation Analysis (CCA) has been widely used to detect frequency-coded SSVEPs due to its high efficiency and robustness. However, the detectability of SSVEPs differs among frequencies due to a power-law distribution of the power spectra of spontaneous electroencephalogram (EEG) signals. This study proposed a new method based on the fact that changes of canonical correlation coefficients for SSVEPs and background EEG signals follow the same trend along frequency. The proposed method defined a normalized canonical correlation coefficient, the ratio of the canonical correlation coefficient for SSVEPs to the mean of the canonical correlation coefficients for background EEG signals, to enhance the frequency detection of SSVEPs. An SSVEP dataset from 13 subjects was used for comparing classification performance between the proposed method and the standard CCA method. Classification accuracy and simulated information transfer rates (ITR) suggest that, in an unsupervised way, the proposed method could considerably improve the frequency detection accuracy of SSVEPs with little computational effort.
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http://dx.doi.org/10.1109/EMBC.2014.6944267 | DOI Listing |
Chaos
January 2025
College of Science, Civil Aviation University of China, Tianjin 300300, China.
Adolescent idiopathic scoliosis (AIS), which typically occurs in patients between the ages of 10 and 18, can be caused by a variety of reasons, and no definitive cause has been found. Early diagnosis of AIS or timely recognition of progression is crucial for the prevention of spinal deformity and the reduction of the risk of surgery or postponement. However, it remains a significant challenge.
View Article and Find Full Text PDFAutophagy
January 2025
Life Sciences Institute, Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.
The multi-step macroautophagy/autophagy process ends with the cargo-laden autophagosome fusing with the lysosome to deliver the materials to be degraded. The metazoan-specific autophagy factor EPG5 plays a crucial role in this step by enforcing fusion specificity and preventing mistargeting. How EPG5 exerts its critical function and how its deficiency leads to diverse phenotypes of the rare multi-system disorder Vici syndrome are not fully understood.
View Article and Find Full Text PDFJMIR Form Res
December 2024
Department of Communication, Stanford University, Stanford, US.
Background: Contrary to popular concerns about the harmful effects of media use on mental health, research on this relationship is ambiguous, stalling advances in theory, interventions, and policy. Scientific explorations of the relationship between media and mental health have mostly found null or small associations, with the results often blamed on the use of cross-sectional study designs or imprecise measures of media use and mental health.
Objective: This exploratory empirical demonstration aimed to answer whether mental health effects are associated with media use experiences by (1) redirecting research investments to granular and intensive longitudinal recordings of digital experiences to build models of media use and mental health for single individuals over the course of one entire year, (2) using new metrics of fragmented media use to propose explanations of mental health effects that will advance person-specific theorizing in media psychology, and (3) identifying combinations of media behaviors and mental health symptoms that may be more useful for studying media effects than single measures of dosage and affect or assessments of clinical symptoms related to specific disorders.
Med Biol Eng Comput
January 2025
Non-Invasive Imaging and Diagnostic Laboratory, Department of Applied Mechanics and Biomedical Engineering, Indian Institute of Technology Madras, Chennai, India.
Detection of early mild cognitive impairment (EMCI) is clinically challenging as it involves subtle alterations in multiple brain sub-anatomic regions. Among different brain regions, the corpus callosum and lateral ventricles are primarily affected due to EMCI. In this study, an improved deep canonical correlation analysis (CCA) based framework is proposed to fuse magnetic resonance (MR) image features from lateral ventricular and corpus callosal structures for the detection of EMCI condition.
View Article and Find Full Text PDFNeuroimage
January 2025
School of Life Science and Technology, Xidian University, Xi'an, Shaanxi 710071, China; Inner Mongolia Key Laboratory of Pattern Recognition and Intelligent Image Processing, School of Information Engineering, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia 014010, China; Engineering Research Center of Molecular and Neuro Imaging Ministry of Education, Xi'an, Shaanxi 710071, China; Xi'an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life Information, School of Life Science and Technology, Xidian University, Xi'an, Shaanxi 710126, China. Electronic address:
Adolescents and young adults are considered a high-risk group for internet gaming disorder (IGD). Early screening for high-risk individuals with IGD and exploring the underlying neural mechanisms is an effective strategy to reduce the harm of IGD. We recruited 219 non-internet gaming addicted college students and evaluated them with magnetic resonance imaging, followed by a two-year longitudinal follow-up.
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