In this paper, we proposed a new method (CSR+OSD) for the extraction of irregular open prostate boundaries in noisy extracorporeal ultrasound image. First, cascaded shape regression (CSR) is used to locate the position of prostate boundary in the images. In CSR, a sequence of random fern predictors are trained in a boosted regression manner, using shape-indexed features to achieve invariance against position variations of prostate boundaries. Afterwards, we adopt optimal surface detection (OSD) to refine the prostate boundary segments across 3D sections globally and efficiently. The proposed method is tested on 162 ECUS images acquired from 8 patients with benign prostate hyperplasia. The method yields a Root Mean Square Distance of 2.11±1.72 mm and a Mean Absolute Distance of 1.61±1.26 mm, which are lower than those of JFilament, an open active contour algorithm and Chan-Vese region based level set model, respectively.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1109/EMBC.2014.6944226 | DOI Listing |
Biol Methods Protoc
December 2024
Medical BioSciences, Radboudumc, Nijmegen 6562 GA, The Netherlands.
Tissue specimens taken from primary tumors or metastases contain important information for diagnosis and treatment of cancer patients. Multiplex imaging allows visualization of heterogeneous cell populations, such as immune cells, in tissue samples. Most image processing pipelines first segment cell boundaries and then measure marker expression to assign cell phenotypes.
View Article and Find Full Text PDFProstate cancer (PC) progresses from benign epithelium through pre-malignant lesions, localized tumors, metastatic dissemination, and castration-resistant stages, with some cases exhibiting phenotype plasticity under therapeutic pressure. However, high-resolution insights into how cell phenotypes evolve across successive stages of PC remain limited. Here, we present the Prostate Cancer Cell Atlas (PCCAT) by integrating ∼710,000 single cells from 197 human samples covering a spectrum of tumor stages.
View Article and Find Full Text PDFJ Clin Med
December 2024
Herston Biofabrication Institute, Metro North Health, Herston, QLD 4029, Australia.
: Prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT), in combination with magnetic resonance imaging (MRI), may enhance the diagnosis and staging of prostate cancer. Image fusion of separately acquired PET/CT and MRI images serve to facilitate clinical integration and treatment planning. This study aimed to investigate different PSMA PET/CT and MRI image fusion workflows for prostate cancer visualisation.
View Article and Find Full Text PDFInt J Urol
December 2024
Department of Urology, Faculty of Medicine, Fukuoka University, Fukuoka, Fukuoka Prefecture, Japan.
Objectives: The aim of the present study was to determine the efficacy and safety of our newly developed ICG-assisted nerve-sparing (NS) robot-assisted radical prostatectomy (RARP) through subjective and objective data.
Methods: This study included 43 NS RARP patients, divided into ICG (23 patients) and non-ICG (20 patients) groups. Immunohistochemical staining with nNOS antibodies was conducted on specimens of resected prostate from the base, middle, and apex to count nNOS-positive cells.
Acad Radiol
December 2024
Department of Radiology, University Hospital Basel, 4051 Basel, Basel-Stadt, Switzerland.
Purpose: To evaluate the effect of lower field strength on quantitative apparent-diffusion-coefficient (ADC) values, contrast of the T2-weighted MR images and the performance of an AI-based segmentation.
Materials And Methods: 25 screening clients (61.6 ± 7.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!