AI Article Synopsis

  • Obsessive Compulsive Disorder (OCD) is a common chronic condition characterized by intrusive thoughts and repetitive behaviors, linked to abnormal brain connectivity in the Default Mode Network (DMN).
  • Recent functional MRI (fMRI) studies have been conducted to compare brain activity between OCD patients and healthy individuals, focusing on different brain conditions.
  • The current study aims to compare classification results from both resting state functional connectivity (rs-FC) and imagination task-related functional connectivity (im-FC), revealing promising outcomes using the same SVM classification method.

Article Abstract

Obsessive Compulsive Disorder (OCD) is a frequent, chronic disorder producing intrusive thoughts which results in repetitive behaviors. It is thought that this psychological disorder occurs due to abnormal functional connectivity in certain regions of the brain called Default Mode Network (DMN) mainly. Recently, functional MRI (FMRI) studies were performed in order to compare the differences in brain activity between patients with OCD and healthy individuals through different conditions of the brain. Our previous study on extraction of disease signature for OCD that is determining the features for discrimination of OCD patients from healthy individuals based on their resting-sate functional connectivity (rs-FC) data had given encouraging results. In the present study, functional data extracted from FMRI images of subjects under imagination task (maintaining an image in mind, im-FC) is considered. The aim of this study is to compare classification results achieved from both resting and task-related (imagination) conditions. This research has shown quite interesting and promising results using the same classification (SVM) method.

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http://dx.doi.org/10.1109/EMBC.2014.6943756DOI Listing

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