Development of a continuous noninvasive blood pressure (cNIBP) monitor that is unobtrusive to patients is an attractive alternative to the cuff based measurements performed on medical-surgical floors in the hospital. Pulse wave velocity (PWV) provides a means to continuously monitor blood pressure in these patients. However, a PWV based cNIBP monitor faces a number of challenges in order to accurately measure blood pressure. In our study, we investigated some of the challenges faced by a body-worn cNIBP monitor (i.e. ViSi Mobile) on data collected on patients undergoing surgery. Results indicated that 1) pulse arrival time (PAT) values from ViSi Mobile were well correlated with PAT values obtained from an invasive reference; 2) the reciprocal of the PAT measurements were linearly correlated with blood pressure but the calibration curve was altered by administration of certain vasoactive substances; and 3) there are deterministic correlations between systolic pressure, diastolic pressure and the corresponding mean arterial pressure over a wide range of blood pressure values.
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