AI Article Synopsis
- Mega-hemocyanin is a large oxygen-carrying protein (13.5 MDa) found in snails.
- Its structure consists of three stacked rings, with each ring composed of ten subunits.
- Recent research using cryo-electron microscopy uncovered an unusual breaking of 5-fold symmetry in the central ring and showed that the packing of the subunits is not uniform.
Article Abstract
Mega-hemocyanin is a 13.5 MDa oxygen transporter found in snails. It is built from three stacked rings involving ten subunits each. The cryo-EM structure of the complex presented by Gatsogiannis and colleagues in this issue of Structure revealed an unexpected breaking of 5-fold symmetry in the central ring and a nonequivalent packing of the subunits.
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| http://dx.doi.org/10.1016/j.str.2014.12.006 | DOI Listing |
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