A synthetic process for constructing an organo-metal nanohybrid is described. This process uses polyaniline as a ligand in order to fabricate magnetic nanoparticles. This nanohybrid shows imaging potential uses as a magnetic resonance imaging contrast agent and a redox-sensing probe simultaneously both in vitro and in vivo.
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http://dx.doi.org/10.1039/c4nr06340f | DOI Listing |
Nanoscale Horiz
December 2024
Intelligent Nanohybrid Materials Laboratory (INML), Department of Chemistry, College of Science and Technology, Dankook University, Cheonan 31116, Republic of Korea.
Over the last two decades, advancements in nanomaterials and nanoscience have paved the path for the emergence of nano-medical convergence science, significantly impacting healthcare. In our review, we highlight how these advancements are applied in various biomedical technologies such as drug delivery systems, bio-imaging for diagnostic and therapeutic purposes. Recently, novel inorganic nanohybrid drugs have been developed, combining multifunctional inorganic nanomaterials with therapeutic agents (known as inorganic medicinal nanoarchitectonics).
View Article and Find Full Text PDFBiosensors (Basel)
October 2024
McComish Department of Electrical Engineering and Computer Science, Jerome J. Lohr College of Engineering, South Dakota State University, Brookings, SD 57007, USA.
Transcutaneous carbon dioxide (TcPCO2) monitoring provides a non-invasive alternative to measuring arterial carbon dioxide (PaCO2), making it valuable for various applications, such as sleep diagnostics and neonatal care. However, traditional transcutaneous monitors are bulky, expensive, and pose risks such as skin burns. To address these limitations, we have introduced a compact, cost-effective CMOS imager-based sensor for TcPCO2 detection by utilizing colorimetric reactions with metal-organic framework (MOF)-based nano-hybrid materials.
View Article and Find Full Text PDFNanomedicine (Lond)
December 2024
Department of Prosthodontics & Materials Science, Saveetha Dental College & Hospitals, Saveetha Institute of Medical & Technical Sciences, Chennai, 600077, Tamil Nadu, India.
Int J Pharm
December 2024
Department of Chemical Engineering. University of Zaragoza, Campus Río Ebro-Edificio I+D, C/ Poeta Mariano Esquillor S/N, Zaragoza 50018, Spain; Instituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, Zaragoza 50009, Spain; Networking Research Center on Bioengineering, Biomaterials and Nanomedicine, CIBER-BBN, Madrid 28029, Spain; Aragon Health Research Institute (IIS Aragon), Zaragoza 50009, Spain.
At the present time, owing to the extremely high growth of microbial resistance to antibiotics and, consequently, the increased healthcare associated costs and the loss of efficacy of current treatments, the development of new therapies against bacteria is of paramount importance. For this reason, in this work, a hybrid synergetic nanovector has been developed, based on the encapsulation of a NIR (near infrared) photosensitive molecule (indocyanine green, ICG) in biodegradable polymeric nanoparticles (NPs). In addition, copper sulfide nanoparticles (CuS NPs), optically sensitive to NIR, were anchored on the polymeric nanoparticle shell in order to boost the generation of reactive oxygen species (ROS) upon NIR irradiation.
View Article and Find Full Text PDFTalanta
February 2025
Maliba Pharmacy College, Uka Tarsadia University, Surat 394350, Gujarat, India. Electronic address:
Molecular diagnosis plays a significant role in detection of biomolecules linked to early stage cancer since it offers greater sensitivity and reliability for identification of biomarker level changes as the disease progresses. The application of vibrational spectroscopy in biomarker detection is defined by the fingerprint spectrum of a molecule originating from single-molecule vibrations. This characteristic makes surface enhanced Raman spectroscopy (SERS) a promising tool for identification of biomarkers.
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