[Inevitable senile death].

Duodecim

Espoo.

Published: January 2015

AI Article Synopsis

  • Many systems important for growth and development become less effective as we age, leading to cell aging and reduced ability to regenerate.
  • Ageing tissues are more prone to chronic diseases linked to aging, although eliminating these diseases would only increase life expectancy by about 15 years.
  • As new therapies advance, accurately diagnosing diseases at the end of life will become more complex, giving rise to the concept of "frailty syndrome."

Article Abstract

Many systems essential to ontogenesis become inappropriate in later life, leading to the ageing of cells and loss of regenerative capacity. Ageing tissues are thus increasingly susceptible to chronic diseases associated with ageing. Upon statistical analysis, the elimination of these diseases would bring about only approximately 15 additional years to the life expectancy. With developing therapies, the making of a precise disease diagnosis upon the eventual death will become increasingly difficult, whereby the term frailty syndrome is utilized.

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