A patient suffering from palindromic rheumatism has recurrent periods of pain and swelling of joints lasting for hours, days or maximally 1 to 2 weeks with an irregular pattern.The diagnosis can be made based on patient history and rheumatoid factor or anti-citrullinated peptide antibodies (positive in approx. 50 to 70%) or on the basis of patient history and objectively established joint swelling. Hydroxychloroquine and other ordinary antirheumatic drugs slow down or may even prevent the progression of palindromic rheumatism into chronic rheumatoid arthritis.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Evaluation of a novel malaria anti-sporozoite vaccine candidate, R21 in Matrix-M adjuvant, in the UK and Burkina Faso: two phase 1, first-in-human trials.
Lancet Microbe
December 2024
Jenner Institute, University of Oxford-NIHR Oxford Biomedical Research Centre, Oxford, UK. Electronic address:
Background: Malaria remains a substantial public health burden among young children in sub-Saharan Africa and a highly efficacious vaccine eliciting a durable immune response would be a useful tool for controlling malaria. R21 is a malaria vaccine comprising nanoparticles, formed from a circumsporozoite protein and hepatitis B surface antigen (HBsAg) fusion protein, without any unfused HBsAg, and is administered with the saponin-based Matrix-M adjuvant. This study aimed to assess the safety and immunogenicity of the malaria vaccine candidate, R21, administered with or without adjuvant Matrix-M in adults naïve to malaria infection and in healthy adults from malaria endemic areas.
View Article and Find Full Text PDFRheumatologic complications of CAR-T Cell therapy. Experience of a single center.
Semin Arthritis Rheum
December 2024
Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Department of Immunology, CDB, Hospital Clínic, Barcelona, Spain.
Introduction: Chimeric Antigen Receptor T-cell (CAR-T) therapy has emerged as a promising treatment for hematological malignancies. However, its association with immune-related complications such as rheumatic complications, is not well defined.
Methods: We conducted a retrospective study to analyze rheumatic complications in 310 patients treated with CAR-T therapy at a single center from January 2020 to May 2024.
Frequency of HLA-DRB1 alleles in palindromic rheumatism in the Azeri population.
Int J Rheum Dis
August 2024
Connective Tissue Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
A Distinct Instance of Palindromic Rheumatism Disguised as Polymyalgia Rheumatica.
Cureus
June 2024
Internal Medicine: Pediatrics, Alabama College of Osteopathic Medicine (ACOM), Dothan, USA.
In this case report, we highlight a rare case of palindromic rheumatism (PR) presenting as polymyalgia rheumatica (PMR). Many challenges and complexities are associated with diagnosing and treating PR. Literature reviews showed only a few case reports of this unique presentation.
View Article and Find Full Text PDFIs interleukin-1 blockade a therapeutic option for patients with palindromic rheumatism?
Clin Rheumatol
August 2024
The Rheumatology Unit, Galilee Medical Center, Road 89, Nahariya, Israel.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!