The role of hypoxia at primary dysmenorrhea, utilizing a novel hypoxia marker--SCUBE1.

Study Objective: To determine the SCUBE1 levels in adolescents with primary dysmenorrhea.

Design: A prospective cross-sectional study.

Setting: A university hospital outpatient clinic, Rize, Turkey.

Participants: A total of 40 adolescent girls, 15 on menses and 25 not on menses.

Interventions And Main Outcome Measures: Demographic features and menstrual history of the participants were assessed and blood samples were obtained for detecting the platelet volume, platelet counts, and SCUBE1 levels of the participants.

Results: No difference was detected between the 2 groups in mean platelet volume, platelet count, and SCUBE1 levels.

Conclusion: Future trials are required to investigate the relation between SCUBE1 levels and primary dysmenorrhea.