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Control of hypercapnia and mortality in home mechanical ventilation: the population-based DISCOVERY study.
ERJ Open Res
November 2024
Centre for Sleep and Wake Disorders, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.
Background: Studies on the survival of patients with home mechanical ventilation (HMV) are sparse. We aimed to analyse the impact of controlled hypercapnia on survival over 27 years among patients with HMV in Sweden.
Study Design And Methods: Population-based cohort study of adult patients starting HMV in the Swedish Registry for Respiratory Failure (Swedevox) during 1996-2022 cross-linked with the National Cause of Death registry.
Cervical osteomyelitis in the setting of multiple comorbidities: a complex anatomical approach. Illustrative case.
J Neurosurg Case Lessons
October 2024
Department of Neurosurgery, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Article Synopsis
- Vertebral osteomyelitis (VO) is a rare but severe spinal infection, accounting for 3%-5% of all osteomyelitis cases, with specific risk factors like age, diabetes, and IV drug use.
- A 54-year-old woman with several health issues developed VO after a fall, initially treated with IV antibiotics, but ultimately required complex surgery due to her deteriorating condition.
- The case emphasizes the necessity for tailored surgical techniques and interdisciplinary care in managing VO, particularly for high-risk patients with complicated medical histories.
Gender Differences in Outcomes of Ambulatory and Hospitalized Patients With Obesity Hypoventilation Syndrome.
Chest
January 2025
Instituto Universitario de Investigación Biosanitaria de Extremadura, Badajoz, Spain; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain; Respiratory Department, Virgen del Puerto Hospital, Plasencia, Cáceres, Spain.
Article Synopsis
- Obesity hypoventilation syndrome (OHS) has high health risks, and this study looks into whether gender affects outcomes for patients with OHS, focusing on both outpatient and hospitalized cases.
- The research analyzed two groups: stable ambulatory patients and hospitalized patients with respiratory failure, assessing gender differences through various statistical methods.
- Findings indicate that while women were generally older and more obese, gender alone did not significantly influence emergency room visits or mortality rates after adjustments for factors like age and obesity.
Obesity hypoventilation syndrome is associated with worse in-hospital outcomes in patients with acute myocardial infarction: A nationwide study.
Respir Med
November 2024
Division of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Article Synopsis
- Obesity hypoventilation syndrome (OHS) is a condition involving obesity, daytime carbon dioxide buildup, and sleep breathing issues, and its effects on acute myocardial infarction (AMI) outcomes are not well understood.
- A study analyzed data from the National Inpatient Sample from 2016 to 2020 to assess outcomes for patients with OHS during heart attacks, specifically ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI).
- Results showed that OHS in NSTEMI patients significantly increased the risk of in-hospital death, cardiac arrest, kidney injury, need for dialysis, and respiratory failure, while STEMI patients with OHS faced higher risks for cardiac arrest
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