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Four carbapenem-resistant gram-negative species carrying distinct carbapenemases in a single patient. | LitMetric
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Four carbapenem-resistant gram-negative species carrying distinct carbapenemases in a single patient.

Baixing Ding Fupin Hu Yang Yang Qinglan Guo Jinwei Huang Minggui Wang

J Clin Microbiol

Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China Key Laboratory of Clinical Pharmacology of Antibiotics, Ministry of Health, Shanghai, China

Published: March 2015

Carbapenem-resistant Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, and Acinetobacter baumannii were isolated from a single patient, each producing different carbapenemases (NDM-1, KPC-2, IMP, and OXA-23, respectively). The NDM-1-producing E. coli strain was preceded by a clonally related carbapenem-susceptible strain a month earlier, suggesting in vivo acquisition of blaNDM-1.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390643PMC
http://dx.doi.org/10.1128/JCM.03623-14DOI Listing

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