AI Article Synopsis
- Xanthogranulomatous cystitis is a rare and benign chronic inflammatory condition that can resemble bladder cancer, leading to diagnostic confusion.
- A case study of a 54-year-old male with abdominal pain and blood in urine illustrates the condition's symptoms and challenges.
- Microscopic analysis revealed large foam histiocytes and specific markers, reinforcing the importance of distinguishing this condition from malignant tumors using immunohistochemical techniques.
Article Abstract
Xanthogranulomatous cystitis is a rare, benign chronic inflammatory disorder with unclear etiology. Since its similar features to bladder neoplasm, it is extremely easy to be mistaken for malignant tumor. We herein reported a case of xanthogranulomatous cystitis in a 54-year-old male who presented with low abdominal pain and painless, total macrohematuria. Microscopy showed proliferation of large foam histiocytes which expressed CD68 and vimentin. Ki-67 showed a lower proliferation index (< 10%). Histopathology and immunohistochemical findings confirmed the diagnosis. This case highlighted the significance of recognizing this unusual lesion and differentiating it from its histological mimics by immunohistochemical staining.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270612 | PMC |
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