[Isolation and in vitro and in vivo characteristics of a clone of a wild Aujeszky disease virus resistant to bromovinyldeoxyuridine].

Ann Rech Vet

Ecole Nationale Vétérinaire de Lyon, Services de maladies contagieuses, France.

Published: December 1989

The antiviral activity of bromovinyldeoxyuridine has been studied on the wild type of pseudorabies virus. A heterogenicity of viral populations has been observed. A resistant clone presented special characteristics both in vitro (large syncytia, round cells) and in vivo (reduced pathogenicity and immunogenic power).

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