Purpose: To evaluate and compare the effectiveness of acellular dermal matrix (ADM) and parotid fascia in preventing Frey's syndrome.
Methods: A literature research was performed using Wanfang Database, Chinese Biological Literature Database, China National Knowledge Infrastructure and Chinese Scientific Journals database of VIP from 2001 to 2013. Relative ratio (RR) was calculated and meta analysis was performed by Review Manager 5.2.
Results: A total of 16 controlled studies were included. Meta analysis showed that the use of ADM and preservation of the parotid fascia could significantly reduce the risk of Frey's syndrome. The subjective incidence was decreased by 71% and 87%, and objective incidence was reduced by 64% and 85%, respectively. Significant difference was found between ADM and parotid fascia in reducing subjective incidence, in which ADM seemed to be more effective.
Conclusions: The present study suggested that parotid fascia should be adopted as an effective method to reduce Frey's syndrome in most circumstances for patients with benign parotid tumors. For those whose parotid fascia could not be preserved, ADM might be another good choice.
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