Virulence markers in Shiga toxin-producing Escherichia coli (STEC) and their association with diseases remain largely unknown. This study determines the importance of 44 genetic markers for STEC (O157 and non-O157) from human clinical cases and their correlation to disease outcome. STEC isolated from a cattle surveillance program were also included. The virulence genes tested were present in almost all O157:H7 isolates but highly variable in non-O157 STEC isolates. Patient age was a significant determinant of clinical outcome.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390646 | PMC |
| http://dx.doi.org/10.1128/JCM.03321-14 | DOI Listing |
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