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[Red Blood Cell Transfusion - Indications, Informed Consent and Associated Risks].
Anasthesiol Intensivmed Notfallmed Schmerzther
January 2025
The aim of red blood cell (RBC) transfusion is to prevent or treat anemic tissue hypoxia in acute or chronic anemia. In 2022, approximately 3.2 million red blood cell transfusions were conducted in Germany.
View Article and Find Full Text PDFImpact of Hypothyroidism in Pregnancy on Feto-Maternal Outcomes: A Prospective Observational Study.
Cureus
November 2024
Department of Pathology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed To Be University), Karad, IND.
Introduction Hypothyroidism represents an endocrine disorder marked by the insufficient production of hormones by the thyroid gland, with significant effects on bodily functions. Its occurrence during pregnancy is of particular concern due to its profound effects on both maternal and fetal health outcomes. Aim To study the impact of hypothyroidism in pregnancy and its correlation with feto-maternal outcomes.
View Article and Find Full Text PDFReconsidering the usual suspects in age-related hematologic disorders: is stem cell dysfunction a root cause of aging?
Exp Hematol
December 2024
Division of Experimental Hematology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Experimental Hematology Group, Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany. Electronic address:
Aging exerts a profound impact on the hematopoietic system, leading to increased susceptibility to infections, autoimmune diseases, chronic inflammation, anemia, thrombotic events, and hematologic malignancies. Within the field of experimental hematology, the functional decline of hematopoietic stem cells (HSCs) is often regarded as a primary driver of age-related hematologic conditions. However, aging is clearly a complex multifaceted process involving not only HSCs but also mature blood cells and their interactions with other tissues.
View Article and Find Full Text PDFThe prevalence of anemia and the factors associated with its severity among children aged 6-59 months in Ghana: A multi-level ordinal logistic regression.
PLoS One
December 2024
Department of Epidemiology, College of Health Sciences and Medicine, Wolaita Sodo University, Soddo, Ethiopia.
Introduction: Anemia is a significant health problem that has a profound impact on young children under the age of five. It can result in severe consequences, such as stunted growth, impaired cognitive and motor development, increased illness, and even death. In Ghana, anemia is the leading cause of child mortality, yet there is a lack of information available on the prevalence of anemia and the factors associated with its severity in children under five in the country.
View Article and Find Full Text PDFLiving with sickle cell in Uganda: A comprehensive perspective on challenges, coping strategies, and health interventions.
Medicine (Baltimore)
December 2024
School of Nursing Science, Kampala International University, Ishaka, Uganda.
Sickle cell anemia (SCA) is a hereditary blood disorder with profound implications for affected individuals, particularly in resource-limited settings such as Uganda. This review explores the multifaceted aspects of SCA in Uganda, focusing on epidemiology, challenges faced by individuals, coping strategies, healthcare disparities, and community support. The study incorporates a thorough examination of the genetic landscape, prevalence, and the impact of SCA on the quality of life in Uganda.
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