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Comparative Performance of Ante-Mortem Diagnostic Assays for the Identification of -Infected Domestic Dogs ().
Pathogens
January 2025
The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian EH25 9RG, UK.
The domestic dog () is a competent host for () infection but no ante mortem diagnostic tests have been fully validated for this species. The aim of this study was to compare the performance of ante mortem diagnostic tests across samples collected from dogs considered to be at a high or low risk of sub-clinical infection. We previously tested a total of 164 dogs at a high risk of infection and here test 42 dogs at a low risk of infection and 77 presumed uninfected dogs with a combination of cell-based and/or serological diagnostic assays previously described for use in non-canid species.
View Article and Find Full Text PDFA systemic review of the utility of antituberculosis therapy for presumed tuberculous uveitis.
BMC Infect Dis
January 2025
Department of Infectious Diseases at the Peter Doherty Institute for Infection and Immunity, Victorian Tuberculosis Program, Melbourne Health, University of Melbourne, Melbourne, Australia.
Background: Uveitis presumed to be secondary to Mycobacterium tuberculosis is a rare but potentially blinding condition. Difficulty in making an accurate diagnosis and the low incidence of TB uveitis (TBU) contribute to the lack of evidence regarding the best management of this condition. This systematic review aims to analyse existing research to provide a summary of the literature regarding the utility of TB therapy for the management of TBU.
View Article and Find Full Text PDFDiagnosing Mycobacterium Kansasii in Shoulder Periprosthetic Joint Infection: A Rare Case Report.
J Orthop Case Rep
January 2025
Department of Orthopedics, University of Illinois College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
Introduction: Periprosthetic joint infections (PJIs) of the shoulder complicate approximately 0.7% of primary and 15.4% of revision shoulder arthroplasties.
View Article and Find Full Text PDFPre-diagnosis and pre-treatment loss to follow-up and associated factors among patients with presumed tuberculosis and those diagnosed in Uganda.
BMC Health Serv Res
December 2024
School of Public Health, Department of Disease Control and Environmental Health, Makerere University, Kampala, Uganda.
Background: Loss to follow-up (LTFU) of patients with presumed tuberculosis (TB) before completing the diagnostic process (pre-diagnosis LTFU) and before initiating treatment for those diagnosed (pre-treatment LTFU) is a challenge in the realization of the End TB Strategy. We assessed the proportion of pre-diagnosis and pre-treatment LTFU and associated factors among patients with presumed TB and those diagnosed in the selected health facilities.
Methods: This was a retrospective cohort study involving a review of routinely collected data from presumptive, laboratory and TB treatment registers from January 2019 to December 2022.
Prevalence of non-tuberculous mycobacteria among people with acid-fast positive presumptive tuberculosis in Mali.
PLoS One
December 2024
Mycobacteriology Unit, Institute of Tropical Medicine, Antwerp, Belgium.
Background: Non-tuberculous mycobacteria (NTM) are environmental agents that can cause opportunistic pulmonary disease in humans and animals, often misdiagnosed as tuberculosis (TB). In this study, we describe the cases of NTM identified during the first national anti-TB drug resistance survey conducted in Mali and explore associated risk factors.
Methods: Sputum was collected from people presenting for pulmonary TB diagnosis from April to December 2019, regardless of age.
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