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Buschke-Lowenstein tumor. | LitMetric

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http://dx.doi.org/10.1097/MAJ.0000000000000413DOI Listing

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The giant condyloma acuminatum, known as the Buschke-Löwenstein tumor (BLT), is an uncommon, slow-growing, cauliflower-like tumor located in the anogenital region. It has a high recurrence rate, is sexually transmitted, and is often linked with immunosuppression. This tumor is commonly associated with human papillomavirus (HPV) infection, making HPV one of the most prevalent sexually transmitted infections affecting the perineal and genital regions.

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GCA, also known as Buschke-Lowenstein tumor, is a rare sexually transmitted disease associated with HPV types 6 and 111. These warts are considered histologically benign, but there is a risk of localized invasion and development of malignancy. This malignant transformation occurs most often in the perianal and vulvar areas, and involvement of other sites is relatively rare2.

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Article Synopsis
  • The Buschke-Löwenstein tumor (BLT) is a rare, exophytic tumor linked to low-risk HPV strains, primarily appearing as a large, cauliflower-like growth in genital areas, which can be locally aggressive and has a notable recurrence rate.
  • A 68-year-old patient with multiple health issues presented with a sizable tumor causing erectile dysfunction and urinary problems, which was successfully surgically excised with reconstruction.
  • Histopathological analysis confirmed the diagnosis, and the patient's recovery underscores the importance of early diagnosis and surgical intervention to manage BLT and prevent complications like malignancy and recurrence.
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Article Synopsis
  • Giant condyloma accuminata, also known as Buschke-Lowenstein tumor, is a rare and large growth resembling a cauliflower, typically found in the anogenital area, and relates to HPV infections.
  • The tumor exists on a spectrum between typical condylomas and squamous cell carcinoma, often resulting in surgical treatment due to its tendency to infiltrate soft tissue and recur.
  • The case presented involves a 40-year-old male with cystic fibrosis who developed this tumor without any known HPV or common risk factors, and he was treated through near-total surgical resection.
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