Regional ventilation/perfusion mismatch pattern in patient with Swyer James (MacLeod's) syndrome.

J Res Med Sci

Department of Nuclear Medicine, Cerrahpaşa Medical Faculty, Istanbul University, Cerrahpasa, Fatih, Istanbul, Turkey.

Published: September 2014

AI Article Synopsis

  • * A case study of a 46-year-old man revealed significant ventilation/perfusion abnormalities in his lungs, particularly on the right side, indicating potential issues such as pulmonary embolism.
  • * While SJMS can show a specific ventilation/perfusion defect, the presence of pulmonary embolism can complicate the diagnosis, requiring careful analysis of lung scintigraphy results.

Article Abstract

Swyer James (McLeod's) syndrome (SJMS) is an uncommon disease, which occurs as a result of childhood bronchiolitis obliterans. Patients may not be diagnosed until later in their life. A 46-year-old man underwent ventilation/perfusion scintigraphy for acute onset of dyspnea. The scan showed markedly diminished ventilation and perfusion unilaterally on the right middle and inferior lobes. However, mismatched ventilation-perfusion pattern was shown on the upper right lobe, which was consistent with pulmonary embolism. Unilaterally matched ventilation/perfusion defect can see in SJMS in lung scintigraphy; however, when pulmoner embolism may accompany, scintigraphy should be carefully examined.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268201PMC

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