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Surface-enhanced Raman spectroscopy: a half-century historical perspective.
Chem Soc Rev
December 2024
State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, School of Electronic Science and Engineering, College of Environment and Ecology, State Key Laboratory of Marine Environmental Science, Department of Physics, iChEM, IKKEM, Xiamen University, Xiamen 361005, China.
Surface-enhanced Raman spectroscopy (SERS) has evolved significantly over fifty years into a powerful analytical technique. This review aims to achieve five main goals. (1) Providing a comprehensive history of SERS's discovery, its experimental and theoretical foundations, its connections to advances in nanoscience and plasmonics, and highlighting collective contributions of key pioneers.
View Article and Find Full Text PDFSelf-assembled peptide-based nanofibers for cardiovascular tissue regeneration.
J Mater Chem B
January 2025
Dipartimento di Scienze del Farmaco, Pharmaceutical Technology and Law Laboratory, Università di Pavia, Via Torquato Taramelli 12, Pavia, Italy.
Cardiovascular diseases are the leading cause of death worldwide, claiming millions of lives every year. Cardiac tissue engineering has emerged as a versatile option for repairing cardiac tissue and helping its regeneration. The use of nanomaterials, particularly nanofiber-based scaffolds combined with biomolecular cues like peptides, has significantly improved the compatibility and efficacy of the scaffolds for cardiac tissue regeneration.
View Article and Find Full Text PDFSelf-Adjuvanting Adenoviral Nanovaccine for Effective T-Cell-Mediated Immunity and Long-Lasting Memory Cell Activation against Tuberculosis.
ACS Infect Dis
November 2024
National Centre for Nanoscience and Nanotechnology, University of Madras, Guindy Campus, Chennai 600 025, Tamil Nadu, India.
An enhanced vaccine is immediately required to swap the more than 100 year-old bacillus Calmette-Guerin (BCG) vaccine against tuberculosis. Here, trimethyl chitosan-loaded inactivated (MST), along with potent adenovirus hexon protein (AdHP), and toll-like receptor (TLR)-1/2 as a nanovaccine, was developed against tuberculosis (TB). The nanoformulation increased the bioavailability of MST and elicited the targeting ability.
View Article and Find Full Text PDFBioinformatics design of peptide binding to the human cardiac troponin I (cTnI) in biosensor development for myocardial infarction diagnosis.
PLoS One
October 2024
School of Electrical Engineering and Informatics, Bandung Institute of Technology, Bandung, West Java, Indonesia.
Cardiovascular disease has reached a mortality rate of 470,000 patients each year. Myocardial infarction accounts for 49.2% of these deaths, and the cTnI protein is a crucial target in diagnosing myocardial infarction.
View Article and Find Full Text PDFExtracellular vesicles-based theranostics for neurodegenerative diseases.
Wiley Interdiscip Rev Nanomed Nanobiotechnol
September 2024
CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing, China.
With the accelerated aging of the global population, the incidence of neurodegenerative diseases (NDDs) is increasing year by year. Because of the presence of the blood-brain barrier (BBB), the low concentration of the biomarkers in peripheral blood and the low penetration rate of the drugs through BBB into brain hinders the development of diagnosis and treatment of NDDs. As an effective mediator to penetrate through BBB in both directions, extracellular vesicles (EVs) have attracted much attention in the early diagnosis and treatment of NDDs because of their superior performance as drug carriers and detection biomarkers.
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