According to a recent national survey of Hospital chief executive officers, financial challenges are their top concern, especially government reimbursement. Moreover, the patient faces greater deductibles forcing hospitals to prioritize price transparency. The Triple Aim program is a tool available to hospital management to help address these challenges. This study indicates that the Triple Aim is valuable to healthcare providers and patients by reducing medical errors, improving healthcare quality, and reducing costs on a per capita basis. Managerial implications are discussed for hospitals and health systems considering this approach to addressing financial challenges.
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http://dx.doi.org/10.1080/00185868.2014.968488 | DOI Listing |
Cureus
December 2024
Department of Anesthesiology, Wake Forest School of Medicine, Winston Salem, USA.
Background and aim The study aimed to investigate the effect of adding perineural adjuvants, clonidine and dexamethasone, to local anesthetic in Superficial Parasternal Intercostal Plane (SPIP) blocks. It was designed as a prospective, randomized, triple-blinded, feasibility trial, conducted at a single-center university hospital. The participants included adult patients who were undergoing cardiac surgery via median sternotomy.
View Article and Find Full Text PDFNatl J Maxillofac Surg
November 2024
Department of Family Dentistry, University of Benin Teaching Hospital, Benin-city, Edo State, Nigeria.
Background: Postoperative throat complications (POTCs) are common and distressing to patients; consensus on their optimum treatment is unclear.
Aim: The aim of the study was to determine the efficacy of a steroid-soaked throat pack on POTCs following oral and maxillofacial surgery.
Materials And Methods: This was a randomized, triple-blinded, controlled clinical study design on all consecutive patients who had endotracheal intubation and pharyngeal throat packs following major oral and maxillofacial surgery.
Geroscience
January 2025
Laboratory of Molecular Basis of Aging, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur St., 02-093, Warsaw, Poland.
One promising strategy to alleviate aging symptoms is the treatment with senolytics that is compounds which selectively eliminate senescent cells. Some therapies aim to reduce symptoms of cellular senescence without senescent cell eradication (senomorphic activity). However, senotherapies raise many questions concerning the selectivity, safety and efficiency of senolitic drugs.
View Article and Find Full Text PDFAnn Thorac Surg
January 2025
Center for Innovation and Outcomes Research, Department of Surgery, Columbia University New York, NY; Columbia HeartSource, Department of Surgery, Columbia University, New York, NY; Division of Cardiac, Thoracic and Vascular Surgery, Columbia University, New York, NY. Electronic address:
Background: Management guidelines for stable three-vessel coronary artery disease have become a subject of debate. We aim to provide a benchmark for the survival of patients with normal ejection fraction, stable three-vessel disease, and elective coronary artery bypass graft (CABG) surgery.
Methods: Data from consecutive patients with normal ejection fraction undergoing elective primary isolated CABG for triple-vessel disease in a diverse 11-center surgical network between 2008 and 2020 were analyzed.
Cell J
January 2025
Department of Molecular Medicine, Institute of Medical Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran. Email:
Objective: The aim of this study was to understand the interactions between tumor-associated mesenchymal stem cells (TA-MSCs) and triple-negative breast cancer (TNBC) cells, which appear to be necessary for developing effective therapies.
Materials And Methods: In this experimental study, MDA-MB-231 and 4T1 TNBC cells were co-cultured with bone marrow-derived MSCs, and TA-MSCs conditioned media (CM) were collected. TA-MSC CM-treated TNBC cells were subjected to migration and invasion assays.
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