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Comprehensive assessment of risk factors and development of novel predictive tools for perioperative hidden blood loss in intertrochanteric femoral fractures: a multivariate retrospective analysis.
Eur J Med Res
December 2024
Department of Orthopedics, The Yangzhou School of Clinical Medicine of Dalian Medical University, Yangzhou, Jiangsu, China.
Objectives: To identify independent risk factors for perioperative hidden blood loss (HBL) in intertrochanteric femoral fractures (ITFs) and to develop a predictive model.
Methods: We enrolled 231 patients with ITFs who underwent proximal femoral nail antirotation (PFNA) surgery at the Orthopedics Department of Northern Jiangsu People's Hospital, Jiangsu Province, China, from January 2021 to December 2023. Hidden blood loss was calculated using the OSTEO formula, and independent risk factors were screened using the Least Absolute Shrinkage and Selection Operator (LASSO) logistic regression.
Assessment of recurrent fever among children undergoing tonsillectomy.
BMC Pediatr
December 2024
Vanderbilt University School of Medicine, Nashville, TN, USA.
Background: Recurrent tonsillitis is a common indication for tonsillectomy in children and has phenotypic overlap with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome. We sought to characterize symptoms associated with PFAPA among children undergoing tonsillectomy.
Methods: Parents/guardians of children undergoing tonsillectomy at Vanderbilt Children's Hospital over a six-week period were queried regarding symptoms of recurrent fever.
Comparison of bioelectrical impedance analysis and dual-energy X-ray absorptiometry for the diagnosis of sarcopenia in the older adults with metabolic syndrome: equipment-specific equation development.
Aging Clin Exp Res
December 2024
Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 82, Gumi-ro 173beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, 13620, Republic of Korea.
Objective: Metabolic syndrome (MetS) and sarcopenia together pose significant health risks, increasing frailty, falls, and fractures in older adults. This study compared muscle mass measurements obtained using two different dual-energy X-ray absorptiometry (DXA) machines and bioelectrical impedance analysis (BIA), and evaluated the accuracy of these measurements in these older adults.
Methods: In this prospective multicenter cohort study, patients aged ≥ 65 years with MetS had their muscle mass assessed using both BIA and DXA.
[ Formula improves liver function of mice with acute-on-chronic liver failure by inhibiting excessive activation of the cGAS-STING signaling pathway].
Nan Fang Yi Ke Da Xue Xue Bao
December 2024
Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Objectives: To explore the role of the cGAS-STING signaling pathway in the therapeutic mechanism of Formula (LXJDHYF) for acute-on-chronic liver failure (ACLF) in mice.
Methods: Thirty C57BL/6 mice were randomly divided into blank control group, model group, low- and high-dose LXJDHYF groups, and H151 (a specific cGAS-STING pathway inhibitor) group (6). In all but the control group, the mice were treated with CCl to induce liver cirrhosis followed by intraperitoneal injections of lipopolysaccharide and D-amino galactose to establish mouse models of ACLF.
[Construction of a diagnostic model and scoring system for central precocious puberty in girls, with external validation].
Zhongguo Dang Dai Er Ke Za Zhi
December 2024
Department of Endocrine Genetics and Metabolism, National Children's Regional Medical Center/Xi'an Children's Hospital, Xi'an 710003, China.
Objectives: To establish an efficient and clinically applicable predictive model and scoring system for central precocious puberty (CPP) in girls, and to develop a diagnostic prediction application.
Methods: A total of 342 girls aged 4 to 9 years with precocious puberty were included, comprising 216 cases of CPP and 126 cases of isolated premature thelarche. Lasso regression was used to screen for predictive factors, and logistic regression was employed to establish the predictive model.
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