Body mass index correlates with pollutant-induced interleukin-1β in sputum and blood.

Ann Allergy Asthma Immunol

Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina Hospitals, Chapel Hill, North Carolina.

Published: March 2015

Murine studies suggest a role for the NLRP3 inflammasome in obesity-driven airway inflammation; human studies are lacking. Our findings demonstrate that human ozone-induced airway and systemic inflammation, measured by IL-1β, correlates with BMI.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352399PMC
http://dx.doi.org/10.1016/j.anai.2014.11.010DOI Listing

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