AI Article Synopsis
- Bifidobacterium longum 105-A is effective at gene transformation and can create gene knockout mutants using a method called homologous recombination.
- The complete genome of strain 105-A has been sequenced, revealing important genetic information.
- The genome contains genes for at least four potential restriction-modification systems, which may enhance its ability to take up foreign DNA.
Article Abstract
Bifidobacterium longum 105-A shows high transformation efficiency and allows for the generation of gene knockout mutants through homologous recombination. Here, we report the complete genome sequence of strain 105-A. Genes encoding at least four putative restriction-modification systems were found in this genome, which might contribute to its transformation efficiency.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271160 | PMC |
| http://dx.doi.org/10.1128/genomeA.01311-14 | DOI Listing |
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