Breast cancer in younger women in Switzerland 1996-2009: a longitudinal population-based study.

Breast

Institute of Social and Preventive Medicine (ISPM), University of Bern, Finkenhubelweg 11, 3012 Bern, Switzerland; Section of Geriatrics, Boston University Medical Center, 88 East Newton St., Boston, MA 02118, USA.

Published: April 2015

Background: Breast cancer (BC) is the most commonly diagnosed cancer and a leading cause of death in younger women.

Methods: We analysed incidence, mortality and relative survival (RS) in women with BC aged 20-49 years at diagnosis, between 1996 and 2009 in Switzerland. Trends are reported as estimated annual percentage changes (EAPC).

Results: Our findings confirm a slight increase in the incidence of BC in younger Swiss women during the period 1996-2009. The increase was largest in women aged 20-39 years (EAPC 1.8%). Mortality decreased in both age groups with similar EAPCs. Survival was lowest among women 20-39 years (10-year RS 73.4%). We observed no notable differences in stage of disease at diagnosis that might explain these differences.

Conclusions: The increased incidence and lower survival in younger women diagnosed with BC in Switzerland indicates possible differences in risk factors, tumour biology and treatment characteristics that require additional examination.

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Source
http://dx.doi.org/10.1016/j.breast.2014.11.004DOI Listing

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