Palladium-catalyzed synthesis of six-membered benzofuzed phosphacycles via carbon-phosphorus bond cleavage.

Org Lett

Department of Applied Chemistry, Faculty of Engineering and ‡Center for Atomic and Molecular Technologies, Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.

Published: January 2015

The palladium-catalyzed synthesis of dibenzofused six-membered phosphacycles via carbon-phosphorus bond cleavage is developed. This method is compatible with a range of functional groups, such as esters, amides, and carbamates, which is in sharp contrast to the limitations of the classical method using organolithium reagents.

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http://dx.doi.org/10.1021/ol503252tDOI Listing

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