Disseminated oligodendroglial-like leptomeningeal tumor with anaplastic progression and presumed extraneural disease: case report.

Clin Imaging

Department of Radiology, University of North Carolina, Chapel Hill, North Carolina; Department of Biomedical Research Imaging Center, University of North Carolina, Chapel Hill, North Carolina. Electronic address:

Published: September 2015

We report the neuroimaging and histopathologic findings of a 12-year-old female patient with a disseminated oligodendroglial-like leptomeningeal tumor with anaplastic progression and presumed extraneural metastatic disease. These tumors may represent distinct pathology primarily seen in pediatric patients. Neuroimaging demonstrates diffuse, progressive enhancement of the leptomeninges often with interval development of intraparenchymal lesions on follow-up. Disease is typically confined to the central nervous system, though diffuse peritoneal disease was seen in our case, possibly through metastatic seeding of the abdomen via ventriculoperitoneal shunt.

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http://dx.doi.org/10.1016/j.clinimag.2014.11.018DOI Listing

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