Endometriosis is a frequent, benign, chronic disease associated with pain and/or infertility. Classically the lesions are found on the pelvic peritoneum, ovary (endometrioma), rectovaginal septum and bladder. Management of endometrioma has evolved over the last few years to individualised treatment. Indeed endometrioma cystectomy can decrease pain and the risk of recurrence but is also associated with a decrease in ovarian reserve. A multi-disciplinary team should manage recto-vaginal or bladder endometriosis. Surgical resection of these lesions must be as complete as possible and can be complex.
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Improving plan quality in cervical cancer brachytherapy using knowledge-based planning for direction modulated brachytherapy tandem applicator.
Brachytherapy
January 2025
Department of Radiation Oncology, Virginia Commonwealth University, Richmond, VA. Electronic address:
Purpose: The bladder and rectal toxicities in cervical cancer brachytherapy are positively correlated with the DVH parameter: D2cc. This study evaluates the feasibility of knowledge-based planning to predict the D2cc, identify suboptimal plans, and improve the plan quality with Direction Modulated Brachytherapy (DMBT) applicators using knowledge-based planning based on linear relationship between overlap distances and D2cc.
Methods: The overlap volume histogram (OVH) method was used to determine the distances for 2 cm of overlap between the Organs at Risks (OAR) and High-Risk Clinical Target Volume (CTV).
Assessing Heterogeneity Effects on Points A, B, and Organs at Risk Doses in High-dose-Rate Brachytherapy for Cervical Cancer - A Comparison of Ir and Co Sources Using Monte Carlo N-Particle 5.
J Med Phys
June 2024
Department of Radiation, Medicine UK Chandler Medical Center, Lexington, KY, USA.
Purpose: The present article deals with investigating the effects of tissue heterogeneity consideration on the dose distribution of Ir and Co sources in high-dose-rate brachytherapy (HDR-BT).
Materials And Methods: A Monte Carlo N-Particle 5 (MCNP5) code was developed for the simulation of the dose distribution in homogeneous and heterogeneous phantoms for cervical cancer patients. The phantoms represented water-equivalent and human body-equivalent tissues.
Protective defunctioning stoma in bowel segmental resection at the time of total hysterectomy for endometriosis: when less is more.
Arch Gynecol Obstet
October 2024
Centre Hospitalier Universitaire de Lille, Service de Chirurgie Gynécologique, 59000, Lille, France.
Purpose: To compare postoperative complications in women undergoing total hysterectomy with segmental resection (TH-SR) for intestinal endometriosis with or without protective defunctioning stoma (PDS) confection.
Methods: Retrospective cohort study conducted at the Gynecologic department of University Hospital of Lille (France) from January 2008 to January 2022 in patients undergone TH-SR for bowel endometriosis.
Results: 100 women were considered for the analysis.
Patterns of practice survey for cervical cancer brachytherapy in Morocco.
Brachytherapy
March 2024
Radiation Oncology Department, Mohammed VI Cancer Treatment Centre, Ibn Rochd Hospital, Casablanca, Morocco; Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.
Purpose: This study surveyed radiation oncologists in Morocco to explore current practices and perspectives on brachytherapy for cervix cancer.
Methods And Materials: A 37-question survey was conducted in April 2023 among 165 Moroccan radiation oncologists using Google Forms.
Results: Of the 93 respondents, 39% treated over 20 patients in 2022 using 3D image-guided brachytherapy (BT) through the HDR technique; 2D techniques were not reported in the last five years.
Predictive Factors for Toxicity After Primary Chemoradiation for Locally Advanced Cervical Cancer: A Systematic Review.
Int J Radiat Oncol Biol Phys
May 2024
Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands.
Purpose: Women with locally advanced cervical cancer (LACC) undergoing primary platinum-based chemoradiotherapy and brachytherapy often experience toxicities. Normal-tissue complication probability (NTCP) models quantify toxicity risk and aid in optimizing radiation therapy to minimize side effects. However, it is unclear which predictors to include in an NTCP model.
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