ER morphology: sculpting with XendoU.

Curr Biol

Cell Biology Section, Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Building 35, Room 2C-913, 9000 Rockville Pike, Bethesda, MD 20892-3738, USA. Electronic address:

Published: December 2014

Endoplasmic reticulum (ER) sheet membranes are covered with ribosomes and RNAs that are involved in protein synthesis. A new study reveals that a calcium-activated endoribonuclease of the EndoU protein family promotes the formation of tubular ER networks, contributing to dynamic shaping of the ER in cells.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585780PMC
http://dx.doi.org/10.1016/j.cub.2014.11.005DOI Listing

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