Synaptic specificity: when the neighbors are away, sensory axons turn promiscuous.

Curr Biol

Department of Molecular, Cell, and Developmental Biology, UCLA, Los Angeles, CA 90095-1606, USA. Electronic address:

Published: December 2014

A new study describes cellular mechanisms establishing synaptic specificity during development and remodeling of a zebrafish mechanosensory organ. Coordination amongst postsynaptic neurons and interactions between presynaptic and postsynaptic cells together promote the segregation of circuits responding to distinct sensory stimuli.

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http://dx.doi.org/10.1016/j.cub.2014.11.004DOI Listing

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