Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
E-mail:
Published: September 2014
Objective: To investigate the effect of smoking on the microRNAs (miRNAs) expression in pneumoconiosis patients.
Methods: Real-time qPCR was used to measure the expression levels of miR-21, miR-200c, miR-16, miR-204, miR-206, miR-155, let-7g, miR-30b, and miR-192 in 36 non-smoking patients with pneumoconiosis and 38 smoking patients with pneumoconiosis, and the differences in expression levels between the two groups were evaluated by two-independent samples t-test.
Results: The expression of miR-192 in serum showed a significant difference between non-smoking and smoking pneumoconiosis patients (P < 0.05), and it decreased gradually in smoking patients with stage I and II pneumoconiosis. In the serum of all pneumoconiosis patients, the expression level of miR-16 was the highest, while the expression level of miR-204 was the lowest.
Conclusion: Pneumoconiosis patients have differential expression of miRNAs in serum, and smoking has an effect on the miRNAs expression in pneumoconiosis patients.
Download full-text PDF |
Source |
---|
Interdiscip Cardiovasc Thorac Surg
January 2025
Critical Care Department, Finis Terrae University. Santiago, Chile.
Silicosis, a fibrotic lung disease caused by crystalline silica inhalation, presents unique challenges in lung transplantation. This case reports an unprecedented complication in a lung transplant recipient with chronic silicosis. A man in his 60 s, post left single-lung transplantation for silica-induced pneumoconiosis, developed acute respiratory deterioration following routine bronchoscopy.
View Article and Find Full Text PDFHealthcare (Basel)
December 2024
Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian National Workers' Compensation Authority (INAIL), Via Stefano Gradi 55, 00143 Rome, Italy.
Objectives: Occupational respiratory diseases represent a major public health concern worldwide. This study analyses the hospitalization costs and characteristics of four major occupational respiratory diseases: malignant mesothelioma (MM), sinonasal cancer (SNC), pneumoconiosis (PN), and hypersensitivity pneumonitis (HP). The findings are situated within the context of Italy's population trends and healthcare system, offering insights into the economic and clinical burden of these diseases.
View Article and Find Full Text PDFPneumoconiosis, caused by inhaling mineral dust, remains a significant occupational disease, despite a declining incidence. Coal workers' pneumoconiosis (CWP), a common subtype, varies in presentation from simple to complicated forms. Differential diagnosis is crucial, especially when CWP manifests as lung masses mimicking malignancy.
View Article and Find Full Text PDFToxicol Lett
January 2025
Department of Public Health,International College,Krirk University, Bangkok 10220, Thailand; School of Public Health, Baotou Medical College, Baotou 014030, Inner Mongolia, PR China. Electronic address:
Rare earth is used extensively around the world, and rare earth particles cause a respiratory disease in workers termed rare earth pneumoconiosis(REP) that have attracted considerable attention. However, the mechanisms of REP, characterized by diffuse pulmonary fibrosis, are elusive. REP progression involves various signaling pathway networks comprising numerous cell types and cytokines.
View Article and Find Full Text PDFTurk J Ophthalmol
December 2024
Kastamonu Training and Research Hospital, Clinic of Ophthalmology, Kastamonu, Türkiye.
We present the case of a patient who came to the emergency department with a significant decrease in vision and dilated pupil in the left eye. Since neurological pathologies were primarily considered, diffusion brain magnetic resonance imaging (MRI) and brain computed tomography (CT) were requested. After the results were reported as normal, we were consulted.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!
© LitMetric 2025. All rights reserved.