Crystalloid inclusions were observed within nongranulated, folliculostellate pituitary cells 72 after estrogen was withdrawn from primed male rats. Like crystalloid inclusions in macrophages reported by others, those observed in this study were associated with structures that appeared to be lysosomes. We suggest that crystalloid inclusions may be the result of phagocytosis, a function of folliculostellate cells proposed by us in a previous study.
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http://dx.doi.org/10.1159/000146757 | DOI Listing |
Crit Care Resusc
December 2024
Department of Intensive Care, Austin Hospital, 145 Studley Road, Heidelberg, Victoria, Australia.
Objective: The optimal timing of vasopressin initiation as an adjunctive vasopressor remains unclear. We aimed to study the association between the timing of vasopressin commencement, pre-specified physiological parameters, and hospital mortality.
Design: We conducted a multicentre, retrospective, observational study.
Pediatr Emerg Care
December 2024
From the Service of Pediatric Emergency Medicine, CHU Sainte-Justine, Montreal.
Introduction: In case of failure of oral rehydration, children with acute gastroenteritis can be hydrated using intravenous (IV) solution. The choice of the intravenous solution itself (solutions containing dextrose versus crystalloids alone) and the glucose quantities to administer are not well established.
Objectives: The main objective of this study was to evaluate the association between the amount of intravenous glucose provided and hospitalization for children with acute gastroenteritis.
Am J Emerg Med
November 2024
Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel; Critical Care Division, Rambam Health Care Campus, Haifa, Israel. Electronic address:
Background: Crystalloid administration during early resuscitation of bleeding trauma patients is recommended by current guidelines, yet evidence supporting this practice is limited. We aimed to evaluate the trends in the utilization of crystalloids during the last decade and to determine the threshold crystalloid volume independently associated with mortality risk in trauma patients at risk of or experiencing shock.
Methods: A retrospective cohort study using data from the Israel National Trauma Registry (January 2013 to December 2022) was conducted.
J Surg Res
December 2024
Firefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, District of Columbia; Department of Surgery, Georgetown University School of Medicine, Washington, District of Columbia; The Burn Center, Department of Surgery, MedStar Washington Hospital Center, Washington, District of Columbia; Department of Plastic and Reconstructive Surgery, Georgetown University School of Medicine, Washington, District of Columbia. Electronic address:
Introduction: Plasma inclusive resuscitation (PIR) uses fresh frozen plasma as an adjunct to crystalloid in the management of burn shock and has potential benefits over other colloids. Yet, safety concerns for transfusion-related acute lung injury (TRALI) exist. The aim of this study evaluated the association between TRALI and PIR in a cohort of severely burn-injured patients using the updated Canadian Blood Services Consensus definitions.
View Article and Find Full Text PDFJ Pediatr Pharmacol Ther
October 2024
Department of Pharmacy (TMA), Le Bonheur Children's Hospital, Memphis TN.
Postural orthostatic tachycardia syndrome (POTS) is a chronic illness with unknown mortality and high morbidity, often diagnosed in the adolescent years. Published literature regarding POTS primarily focuses on the adult population, and guidance on treatment in pediatrics is sparse. The purpose of this clinical review is to evaluate the current literature on the management of POTS in pediatric patients.
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