Comparative estimation of immediate and late follow-up results of treatment was con- ducted in 520 patients, suffering cancer of the colonic right half, including coecum - in 227 (43.7% ± 2.1%), colon ascendum - in 159(30.7% ± 2.0%), right colonic flexure - in 66 (12.9% ± 1.3%), right half of colon transversum - in 66 (12.9% ± 4.2%). In 463 (89.0% ± 1.4%) patients radical operations were performed, while in 57 (11.0% ± 1.7%) - the symptomatic. After radical operations 8 (1.7% ± 0.5%) patients died, and after the symptomatic - 3 (5.3% ± 3.0%). Definite surgical treatment was performed in 258 (60,8% ± 2,4%) patients, the combined one - in 166 (39.2% ± 2.4%). Five-year survival have constituted (64.2% ± 5.5%) for the patients, operated on for the colon ascendumcancer, and (19.1% ± 5.7%) - for cancer of right colonic flexure; while after combined treatment - (40.4% ± 5.8%) in patients, operated on for cancer of coecum, (29.4% ± 11.9%) - right half of colon transversum; ten-year survival have constituted (16.8% ± 2.7%) for the patients, who were radically operated for cancer of coecum, and (4.8% ± 2.6%) - for cancer of right colonic flexure (p<0,005). Late follow-up results of radical treatment of the colonic right half depends essentially on localization and degree of the cancer spread.
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Front Med (Lausanne)
January 2025
Institute of Gastroenterology, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Ischemic colitis (IC) is a multifaceted condition that often manifests with nonspecific symptoms such as abdominal pain and bloody diarrhea, particularly in older adults with vascular risk factors. Diagnosis is supported by elevated levels of white blood cells, lactate, and C-reactive protein (CRP). Computed tomography (CT) imaging typically reveals wall thickening and fat stranding in watershed areas.
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D'Or Institute for Research and Education, Digestive Surgery Residency Program - Rio de Janeiro (RJ), Brazil.
In patients with synchronic liver colorectal metastasis, resection of the primary tumor and liver metastases is the only potentially curative strategy. In such cases, there is no consensus on whether resection of the primary tumor and metastases should be performed simultaneously or whether a staged approach should be performed (resection of the primary tumor and after, hepatectomy, or hepatectomy first). Patients with no bowel occlusion and with extensive liver disease are advised neoadjuvant oncological therapy.
View Article and Find Full Text PDFAssay Drug Dev Technol
January 2025
Institute of Pharmaceutical Research, GLA University, Mathura, India.
mSystems
January 2025
Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou, Guizhou Medical University, Guiyang, China.
Unlabelled: The gut microbiota is closely associated with inflammatory bowel disease (IBD) and colorectal cancer (CRC). Probiotics such as (CB) or (AKK) have the potential to treat inflammatory bowel disease (IBD) or colorectal cancer (CRC). However, research on the combined therapeutic effects and immunomodulatory mechanisms of CB and AKK in treating IBD or CRC has never been studied.
View Article and Find Full Text PDFColorectal Dis
January 2025
Ellen Leifer Shulman and Steven Shulman Digestive Disease Centre, Cleveland Clinic Florida, Weston, Florida, USA.
Aim: Lymphovascular invasion (LVI) is a well-known risk factor in colorectal cancer that is associated with a worse prognosis. The present study aimed to assess the characteristics of patients with LVI-positive colon cancer according to the status of nodal metastases and to study the association between LVI-nodal status and survival.
Method: This retrospective study assessed the association between LVI and lymph node metastases in colon cancer, using data from the National Cancer Database.
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